Please see below for studies on the active ingredients
Choline
https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2011.2056
KSM-66
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/
PPS
Lions Mane
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987239/